Stock Fundamentals

Company Information

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Company Name
Annovis Bio Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NYSE
ISIN: US03615A1088
CIK: 0001477845
CUSIP: 03615A108
Currency: USD
Full Time Employees: 8
Phone: 484 875 3192
Website: https://www.annovisbio.com
Fiscal Year End: December
IPO Date: Feb 12, 2010
Description:

Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration in the United States. The company's lead product candidate is Buntanetap, which is in phase 2/3 to treat alzheimer's disease, as well as in phase 3 to treat parkinson's disease; and is in phase 2 clinical trial to treat lewy body dementia. It also develops ANVS405, which is in phase 2 and 3 clinical trials for the treatment of traumatic brain injury and/or stroke; and ANVS301, which finished phase 1 clinical trial to treat later stages of alzheimer's disease and dementia. The company was incorporated in 2008 and is headquartered in Malvern, Pennsylvania.

Address:

101 Lindenwood Drive, Malvern, PA, United States, 19355

Directors & Officers

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Name Title Year Born
Dr. Maria L. Maccecchini Ph.D. Founder, CEO, President & Executive Director 1951
Mr. Mark Patrick Guerin C.M.A., CPA, CFM Chief Financial Officer 1969
Dr. Cheng Fang Ph.D. Senior Vice President of Research & Development NA
Ms. Eve M. Damiano M.S., RAC Senior Vice President of Regulatory Operations NA
Ms. Melissa Gaines Senior Vice President of Clinical Operations NA
Mr. Blake Jensen M.B.A. Head of Quality NA
Ms. Hilda Maibach Senior Vice President of Statistics NA

Institutional Holders

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Holder Name Shares Date Reported % Out Value % Change
Vanguard Group Inc 923.20K Dec 31, 2025 3.48% $0.00 25.09%
Two Sigma Investments LLC 551.84K Dec 31, 2025 2.08% $0.00 0.00%
Susquehanna International Group, LLP 218.42K Sep 30, 2025 0.82% $0.00 32.73%
Geode Capital Management, LLC 184.15K Sep 30, 2025 0.69% $0.00 0.47%
Citadel Advisors Llc 174.35K Sep 30, 2025 0.66% $0.00 494.51%
Northern Trust Corp 121.06K Sep 30, 2025 0.46% $0.00 103.41%
Merit Financial Group, LLC 81.32K Dec 31, 2025 0.31% $0.00 0.00%
BlackRock Inc 80.68K Sep 30, 2025 0.30% $0.00 0.00%
Omers Administration Corp 62.10K Dec 31, 2025 0.23% $0.00 0.00%
Two Sigma Advisers, LLC 45.22K Dec 31, 2025 0.17% $0.00 0.00%
Greenwich Wealth Management LLC 42.40K Dec 31, 2025 0.16% $0.01 -10.55%
Wescott Financial Advisory Group, LLC 41.61K Dec 31, 2025 0.16% $0.01 0.00%
First National Trust Co 40.00K Dec 31, 2025 0.15% $0.00 166.67%
State Street Corp 38.44K Sep 30, 2025 0.15% $0.00 0.00%
Group One Trading, LP 34.63K Sep 30, 2025 0.13% $0.00 9.34%
JPMorgan Chase & Co 29.80K Sep 30, 2025 0.11% $0.00 100.00%
Lokken Investment Group LLC 29.25K Sep 30, 2025 0.11% $0.02 0.04%
XTX Topco Ltd 28.85K Sep 30, 2025 0.11% $0.00 0.00%
Oakmont Partners, LLC 26.20K Dec 31, 2025 0.10% $0.00 0.00%
Bridgeway Capital Management, LLC 24.40K Dec 31, 2025 0.09% $0.00 25.77%

Shares Statistics

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Shares Outstanding: 26.50M
Shares Float: 22.41M
% Insiders: 1,545.00%
% Institutions: 2,023.00%
Short % Float: 11.57%

🏆 Top 10 Institutional Holders

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Rank Holder Name Shares Held % of Shares Change Date Reported
1 Vanguard Group Inc 923.20K 3.48% ▲ 25.09% Dec 31, 2025
2 Two Sigma Investments LLC 551.84K 2.08% ▲ 0.00% Dec 31, 2025
3 Susquehanna International Group, LLP 218.42K 0.82% ▲ 32.73% Sep 30, 2025
4 Geode Capital Management, LLC 184.15K 0.69% ▲ 0.47% Sep 30, 2025
5 Citadel Advisors Llc 174.35K 0.66% ▲ 494.51% Sep 30, 2025
6 Northern Trust Corp 121.06K 0.46% ▲ 103.41% Sep 30, 2025
7 Merit Financial Group, LLC 81.32K 0.31% ▲ 0.00% Dec 31, 2025
8 BlackRock Inc 80.68K 0.30% ▲ 0.00% Sep 30, 2025
9 Omers Administration Corp 62.10K 0.23% ▲ 0.00% Dec 31, 2025
10 Two Sigma Advisers, LLC 45.22K 0.17% ▲ 0.00% Dec 31, 2025

Valuation Metrics

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Enterprise Value: $49.91M
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

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Market Cap: $66.79M
Book Value: $0.65
Earnings/Share: $-1.43
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -105.88%
ROE (TTM): -246.14%
Revenue (TTM): $0.00
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 0.00%

Stock Price History

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1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Download Financials (Excel)

Financial Charts

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Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

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Financial Ratios

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Earnings History

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Balance Sheet (Yearly)

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Financial Ratios

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Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 5.37x 0.00x 0.20x N/A N/A
2024-12-31 3.59x 0.00x 0.33x -14.40x 0.00x
2023-12-31 2.39x 0.00x 1.76x N/A 0.00x
2022-12-31 4.68x 0.00x 0.21x -139.63x 0.00x
2021-12-31 30.54x 0.00x 0.03x -1,090.16x 0.00x
2020-12-31 14.04x 0.00x 0.07x -0.14x 0.00x
2019-12-31 0.37x -0.06x 8.68x -0.04x -0.63x
2018-12-31 0.09x 0.00x 149.92x -10,817.23x 0.00x
2017-12-31 0.73x 0.00x 20.46x -8,124.20x 0.00x
2012-12-31 9.14x 0.00x 0.06x N/A 0.00x
2011-12-31 1.85x 0.00x 0.34x N/A 0.00x
2010-12-31 2.35x 0.00x 0.25x N/A 0.00x
2009-12-31 2.66x 0.00x 0.03x N/A 0.00x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Dec 08, 2025 Michael B Hoffman N/A Purchase 45.00K $4.31 $193.95K
Nov 24, 2025 Michael B Hoffman N/A Purchase 39.20K $4.08 $159.94K
Nov 21, 2025 Michael B Hoffman N/A Purchase 20.00K $3.50 $70.00K
Nov 14, 2025 Michael B Hoffman N/A Purchase 15.00K $2.11 $31.65K
Oct 28, 2025 Maria-Luisa Maccecchini N/A Purchase 97.56K $2.05 $200.00K
Oct 28, 2025 Michael B Hoffman N/A Purchase 975.61K $2.05 $2.00M

📦 Raw API Data (JSON Explorer)

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