FULC.US Fundamentals - AlphaKey Financial

People

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Directors & Officers

Name	Title	Year Born
Mr. Alexander C. Sapir	CEO, President & Director	1967
Mr. Alan A. Musso C.M.A., CPA	CFO, Treasurer & Principal Accounting Officer	1962
Mr. Curtis G. Oltmans J.D.	Chief Legal Officer, Head of External Affairs & Corporate Secretary	1963
Dr. Bradley E. Bernstein M.D., Ph.D.	Founder	NA
Dr. Michael R. Green	Founder	NA
Dr. Rudolf Jaenisch M.D., Ph.D.	Founder	NA
Dr. Tsun-Huei Lee M.D., Ph.D.	Founder	1964
Dr. Danny Reinberg	Founder	NA
Dr. Iain Fraser DPHIL	Senior Vice President of Early Development	NA
Bobby Riehle Ph.D.	Head of Program Strategy & Vice President	NA
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Jan 02, 2026	Robert J Gould	N/A	Sale	15.00K	$11.87	$178.05K	SEC
Dec 08, 2025	Ra Capital Management, L.P.	N/A	Sale	4.18M	$13.98	$58.37M	SEC
Nov 19, 2025	Robert J Gould	N/A	Sale	15.00K	$11.03	$165.45K	SEC
May 08, 2025	Greg Tourangeau	N/A	Sale	498.00	$5.06	$2.52K	SEC
Shareholders

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Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
Nantahala Capital Management, LLC	10.95M	Jun 30, 2026	14.34%	$0.67	259.01%
BlackRock Inc	8.82M	Jun 30, 2026	11.55%	$0.00	63.70%
EcoR1 Capital, LLC	6.55M	Jun 30, 2026	8.58%	$1.17	0.00%
TANG CAPITAL MANAGEMENT LLC	6.52M	Jun 30, 2026	8.54%	$1.08	0.00%
Suvretta Capital Management, LLC	3.68M	Jun 30, 2026	4.82%	$0.25	-43.90%
D. E. Shaw & Co LP	3.04M	Jun 30, 2026	3.99%	$0.01	87.55%
Citadel Advisors Llc	2.70M	Jun 30, 2026	3.54%	$0.00	109.25%
Vanguard Capital Management, LLC	2.70M	Jun 30, 2026	3.53%	$0.00	0.16%
Jane Street Group LLC	2.22M	Jun 30, 2026	2.90%	$0.00	614.36%
State Street Corp	2.04M	Jun 30, 2026	2.67%	$0.00	31.43%
Adage Capital Partners Gp LLC	2.00M	Jun 30, 2026	2.62%	$0.01	400.00%
GSK PLC	1.79M	Jun 30, 2026	2.34%	$1.09	0.00%
Qube Research & Technologies	1.75M	Jun 30, 2026	2.29%	$0.01	79.38%
Assenagon Asset Management SA	1.67M	Jun 30, 2026	2.19%	$0.00	39.92%
Renaissance Technologies Corp	1.65M	Jun 30, 2026	2.16%	$0.01	12,016.18%
ADAR1 Capital Management LLC	1.57M	Jun 30, 2026	2.05%	$0.26	1,098.70%
Millennium Management LLC	1.49M	Jun 30, 2026	1.95%	$0.00	316.81%
Geode Capital Management, LLC	1.43M	Jun 30, 2026	1.88%	$0.00	-3.66%
Marshall Wace Asset Management Ltd	1.36M	Jun 30, 2026	1.78%	$0.00	0.00%
UBS Group AG	1.25M	Jun 30, 2026	1.64%	$0.00	297.83%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Vanguard MStar Total Stk Mkt Idx Invest	2.07M	2.72%	▲ 0.00%	Sep 30, 2026
2	BlackRock Advantage Small Cap Core Instl	1.74M	2.28%	▲ 13.96%	Sep 30, 2026
3	iShares Russell 2000 ETF	1.70M	2.23%	▼ 0.41%	Oct 29, 2026
4	Fidelity Small Cap Index	646.38K	0.85%	▲ 0.30%	Jul 31, 2026
5	iShares Russell 2000 Value ETF	625.27K	0.82%	▼ 0.31%	Oct 28, 2026
6	Fidelity Enhanced Small Cap Core ETF	598.78K	0.78%	▲ 0.27%	Oct 29, 2026
7	iShares Biotechnology ETF	576.71K	0.76%	▼ 0.19%	Oct 29, 2026
8	Vanguard Russell 2000 ETF	396.02K	0.52%	▲ 16.46%	Sep 30, 2026
9	Schwab US Small-Cap ETF™	326.61K	0.43%	▲ 0.00%	Oct 30, 2026
10	Strategic Advisers U.S. Total Stock	292.64K	0.38%	▲ 34.64%	Aug 31, 2026
Financial Highlights

▼
Market Cap: $287.96M
EBITDA: $-85.40M
Book Value: $4.07
Earnings/Share: $-1.21
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -19.59%
ROE (TTM): -32.38%
Revenue (TTM): $0.00
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): -100.00%
Valuation Metrics

Enterprise Value: $-27.89M
Trailing P/E: 0.00
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 76.38M
Shares Float: 63.49M
% Insiders: 3.35%
% Institutions: 102.10%
Shares Short: 6.76M
Shares Short (Prior Month): 7.11M
Short Ratio: 4.44
Short % Float: 8.94%
Stock Price History

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Open price histogram Stock regimes
1 Year Price History

3 Years Price History

10 Years Price History

Max Price History

Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$0.00
Cost of Goods Sold
adjust
$-1.39M
Gross Profit
subtotal
$-1.39M
SG&A
adjust
$-28.67M
R&D
adjust
$-56.10M
Operating Income
subtotal
$-84.77M
Other / Non-Operating Items
adjust
$9.89M
Net Income
subtotal
$-74.88M
Earnings Per Share (EPS) History

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Financial Ratios

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📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "FULC",
        "Type": "Common Stock",
        "Name": "Fulcrum Therapeutics Inc",
        "Exchange": "NASDAQ",
        "OperatingMIC": "XNAS",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG00DDY1RK9",
        "ISIN": null,
        "LEI": null,
        "PrimaryTicker": "FULC.US",
        "CUSIP": null,
        "CIK": "0001680581",
        "EmployerIdNumber": null,
        "FiscalYearEnd": "December",
        "IPODate": "2019-07-18",
        "InternationalDomestic": null,
        "Sector": "Healthcare",
        "Industry": "Biotechnology",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Pharmaceuticals",
        "GicSubIndustry": "Pharmaceuticals",
        "HomeCategory": "Domestic",
        "IsDelisted": false,
        "Description": "Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers programs for the treatment of diamond-blackfan anemia, Bone Marrow Failure Syndromes, novel fetal hemoglobin inducers, fibrotic disorders. It has licensce agreement with CAMP4 which includes certain small molecule compounds, composition of matter and method of use patent rights, and know-how to research, develop, manufacture, use, and commercialize. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.",
        "Address": "26 Landsdowne Street, Cambridge, MA, United States, 02139",
        "AddressData": {
            "Street": "26 Landsdowne Street",
            "City": "Cambridge",
            "State": "MA",
            "Country": "United States",
            "ZIP": "02139"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Mr. Alexander C. Sapir",
                "Title": "CEO, President & Director",
                "YearBorn": "1967"
            },
            {
                "Name": "Mr. Alan A. Musso C.M.A., CPA",
                "Title": "CFO, Treasurer & Principal Accounting Officer",
                "YearBorn": "1962"
            },
            {
                "Name": "Mr. Curtis G. Oltmans J.D.",
                "Title": "Chief Legal Officer, Head of External Affairs & Corporate Secretary",
                "YearBorn": "1963"
            },
            {
                "Name": "Dr. Bradley E. Bernstein M.D., Ph.D.",
                "Title": "Founder",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Michael R. Green",
                "Title": "Founder",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Rudolf  Jaenisch M.D., Ph.D.",
                "Title": "Founder",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Tsun-Huei  Lee M.D., Ph.D.",
                "Title": "Founder",
                "YearBorn": "1964"
            },
            {
                "Name": "Dr. Danny  Reinberg",
                "Title": "Founder",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Iain  Fraser DPHIL",
                "Title": "Senior Vice President of Early Development",
                "YearBorn": "NA"
            },
            {
                "Name": "Bobby  Riehle Ph.D.",
                "Title": "Head of Program Strategy & Vice President",
                "YearBorn": "NA"
            }
        ],
        "Phone": "617 651 8851",
        "WebURL": "https://www.fulcrumtx.com",
        "LogoURL": "/img/logos/US/FULC.png",
        "FullTimeEmployees": 9,
        "UpdatedAt": "2026-11-05"
    },
    "Highlights": {
        "MarketCapitalization": 287959968,
        "MarketCapitalizationMln": 287.96,
        "EBITDA": -85396000,
        "PERatio": null,
        "PEGRatio": null,
        "WallStreetTargetPrice": 3.6667,
        "BookValue": 4.073,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": -1.21,
        "EPSEstimateCurrentYear": -0.6559,
        "EPSEstimateNextYear": -0.5476,
        "EPSEstimateNextQuarter": -0.1532,
        "EPSEstimateCurrentQuarter": -0.2238,
        "MostRecentQuarter": "2026-06-30",
        "ProfitMargin": 0,
        "OperatingMarginTTM": 0,
        "ReturnOnAssetsTTM": -0.1959,
        "ReturnOnEquityTTM": -0.3238,
        "RevenueTTM": 0,
        "RevenuePerShareTTM": 0,
        "QuarterlyRevenueGrowthYOY": -1,
        "GrossProfitTTM": -56103000,
        "DilutedEpsTTM": -1.21,
        "QuarterlyEarningsGrowthYOY": 0
    },
    "Valuation": {
        "TrailingPE": 0,
        "ForwardPE": 0,
        "PriceSalesTTM": 2.6567,
        "PriceBookMRQ": 0.9194,
        "EnterpriseValue": -27893515,
        "EnterpriseValueRevenue": 117.3999,
        "EnterpriseValueEbitda": -3.0945
    },
    "SharesStats": {
        "SharesOutstanding": 76381948,
        "SharesFloat": 63488473,
        "PercentInsiders": 3.3489999999999998,
        "PercentInstitutions": 102.095,
        "SharesShort": 6756520,
        "SharesShortPriorMonth": 7110810,
        "ShortRatio": 4.44,
        "ShortPercentOutstanding": null,
        "ShortPercentFloat": 0.0894
    },
    "Technicals": {
        "Beta": 2.77,
        "52WeekHigh": 15.7399,
        "52WeekLow": 2.83,
        "50DayMA": 3.7557,
        "200DayMA": 5.798,
        "SharesShort": 6756520,
        "SharesShortPriorMonth": 7110810,
        "ShortRatio": 4.44,
        "ShortPercent": 0.0894
    },
    "SplitsDividends": {
        "ForwardAnnualDividendRate": 0,
        "ForwardAnnualDividendYield": 0,
        "PayoutRatio": 0,
        "DividendDate": null,
        "ExDividendDate": null,
        "LastSplitFactor": "",
        "LastSplitDate": "0000-00-00",
        "NumberDividendsByYear": []
    },
    "AnalystRatings": {
        "Rating": 2.8,
        "TargetPrice": 3.6667,
        "StrongBuy": 0,
        "Buy": 0,
        "Hold": 4,
        "Sell": 1,
        "StrongSell": 0
    },
    "Holders": {
        "Institutions": [
            {
                "name": "Nantahala Capital Management, LLC",
                "date": "2026-06-30",
                "totalShares": 14.336,
                "totalAssets": 0.6659,
                "currentShares": 10950080,
                "change": 7900040,
                "change_p": 259.0143
            },
            {
                "name": "BlackRock Inc",
                "date": "2026-06-30",
                "totalShares": 11.5528,
                "totalAssets": 0.0005,
                "currentShares": 8824259,
                "change": 3433666,
                "change_p": 63.6974
            },
            {
                "name": "EcoR1 Capital, LLC",
                "date": "2026-06-30",
                "totalShares": 8.5751,
                "totalAssets": 1.1656,
                "currentShares": 6549866,
                "change": 6549866,
                "change_p": 0
            },
            {
                "name": "TANG CAPITAL MANAGEMENT LLC",
                "date": "2026-06-30",
                "totalShares": 8.5379,
                "totalAssets": 1.084,
                "currentShares": 6521412,
                "change": 6521412,
                "change_p": 0
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            {
                "name": "Suvretta Capital Management, LLC",
                "date": "2026-06-30",
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                "currentShares": 3680921,
                "change": -2880190,
                "change_p": -43.8979
            },
            {
                "name": "D. E. Shaw & Co LP",
                "date": "2026-06-30",
                "totalShares": 3.9857,
                "totalAssets": 0.0053,
                "currentShares": 3044385,
                "change": 1421104,
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            },
            {
                "name": "Citadel Advisors Llc",
                "date": "2026-06-30",
                "totalShares": 3.5408,
                "totalAssets": 0.0011,
                "currentShares": 2704505,
                "change": 1412019,
                "change_p": 109.2483
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                "name": "Vanguard Capital Management, LLC",
                "date": "2026-06-30",
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                "currentShares": 2697216,
                "change": 4268,
                "change_p": 0.1585
            },
            {
                "name": "Jane Street Group LLC",
                "date": "2026-06-30",
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                "currentShares": 2217498,
                "change": 1907081,
                "change_p": 614.361
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            {
                "name": "State Street Corp",
                "date": "2026-06-30",
                "totalShares": 2.6669,
                "totalAssets": 0.0002,
                "currentShares": 2037025,
                "change": 487174,
                "change_p": 31.4336
            },
            {
                "name": "Adage Capital Partners Gp LLC",
                "date": "2026-06-30",
                "totalShares": 2.6184,
                "totalAssets": 0.0103,
                "currentShares": 2000000,
                "change": 1600000,
                "change_p": 400
            },
            {
                "name": "GSK PLC",
                "date": "2026-06-30",
                "totalShares": 2.3379,
                "totalAssets": 1.0853,
                "currentShares": 1785714,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Qube Research & Technologies",
                "date": "2026-06-30",
                "totalShares": 2.2891,
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                "currentShares": 1748467,
                "change": 773728,
                "change_p": 79.378
            },
            {
                "name": "Assenagon Asset Management SA",
                "date": "2026-06-30",
                "totalShares": 2.1869,
                "totalAssets": 0.0038,
                "currentShares": 1670408,
                "change": 476535,
                "change_p": 39.915
            },
            {
                "name": "Renaissance Technologies Corp",
                "date": "2026-06-30",
                "totalShares": 2.1573,
                "totalAssets": 0.0083,
                "currentShares": 1647800,
                "change": 1634200,
                "change_p": 12016.1765
            },
            {
                "name": "ADAR1 Capital Management LLC",
                "date": "2026-06-30",
                "totalShares": 2.049,
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                "currentShares": 1565029,
                "change": 1434469,
                "change_p": 1098.7048
            },
            {
                "name": "Millennium Management LLC",
                "date": "2026-06-30",
                "totalShares": 1.9452,
                "totalAssets": 0.002,
                "currentShares": 1485803,
                "change": 1129332,
                "change_p": 316.8089
            },
            {
                "name": "Geode Capital Management, LLC",
                "date": "2026-06-30",
                "totalShares": 1.875,
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                "currentShares": 1432133,
                "change": -54409,
                "change_p": -3.6601
            },
            {
                "name": "Marshall Wace Asset Management Ltd",
                "date": "2026-06-30",
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                "totalAssets": 0.0039,
                "currentShares": 1358423,
                "change": 1358423,
                "change_p": 0
            },
            {
                "name": "UBS Group AG",
                "date": "2026-06-30",
                "totalShares": 1.6416,
                "totalAssets": 0.0006,
                "currentShares": 1253909,
                "change": 938724,
                "change_p": 297.8327
            }
        ],
        "Funds": [
            {
                "name": "Vanguard MStar Total Stk Mkt Idx Invest",
                "date": "2026-09-30",
                "totalShares": 2.7157,
                "totalAssets": 0.0003,
                "currentShares": 2074332,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "BlackRock Advantage Small Cap Core Instl",
                "date": "2026-09-30",
                "totalShares": 2.2754,
                "totalAssets": 0.1201,
                "currentShares": 1737977,
                "change": 212947,
                "change_p": 13.9635
            },
            {
                "name": "iShares Russell 2000 ETF",
                "date": "2026-10-29",
                "totalShares": 2.228,
                "totalAssets": 0.0084,
                "currentShares": 1701758,
                "change": -6930,
                "change_p": -0.4056
            },
            {
                "name": "Fidelity Small Cap Index",
                "date": "2026-07-31",
                "totalShares": 0.8462,
                "totalAssets": 0.0068,
                "currentShares": 646379,
                "change": 1946,
                "change_p": 0.302
            },
            {
                "name": "iShares Russell 2000 Value ETF",
                "date": "2026-10-28",
                "totalShares": 0.8186,
                "totalAssets": 0.0167,
                "currentShares": 625266,
                "change": -1916,
                "change_p": -0.3055
            },
            {
                "name": "Fidelity Enhanced Small Cap Core ETF",
                "date": "2026-10-29",
                "totalShares": 0.7839,
                "totalAssets": 0.0329,
                "currentShares": 598775,
                "change": 1612,
                "change_p": 0.2699
            },
            {
                "name": "iShares Biotechnology ETF",
                "date": "2026-10-29",
                "totalShares": 0.755,
                "totalAssets": 0.0189,
                "currentShares": 576710,
                "change": -1092,
                "change_p": -0.189
            },
            {
                "name": "Vanguard Russell 2000 ETF",
                "date": "2026-09-30",
                "totalShares": 0.5185,
                "totalAssets": 0.0083,
                "currentShares": 396017,
                "change": 55983,
                "change_p": 16.4639
            },
            {
                "name": "Schwab US Small-Cap ETF\u2122",
                "date": "2026-10-30",
                "totalShares": 0.4276,
                "totalAssets": 0.0055,
                "currentShares": 326605,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Strategic Advisers U.S. Total Stock",
                "date": "2026-08-31",
                "totalShares": 0.3831,
                "totalAssets": 0.0011,
                "currentShares": 292639,
                "change": 75292,
                "change_p": 34.6414
            },
            {
                "name": "Fidelity Extended Market Index",
                "date": "2026-08-31",
                "totalShares": 0.3605,
                "totalAssets": 0.0027,
                "currentShares": 275348,
                "change": 109506,
                "change_p": 66.0303
            },
            {
                "name": "Vanguard Strategic Small-Cap Equity Inv",
                "date": "2026-09-30",
                "totalShares": 0.3208,
                "totalAssets": 0.0278,
                "currentShares": 245027,
                "change": 53906,
                "change_p": 28.2052
            },
            {
                "name": "iShares Micro-Cap ETF",
                "date": "2026-10-29",
                "totalShares": 0.2711,
                "totalAssets": 0.0621,
                "currentShares": 207055,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "BlackRock Advantage SMID Cap Instl",
                "date": "2026-09-30",
                "totalShares": 0.2702,
                "totalAssets": 0.0752,
                "currentShares": 206416,
                "change": 17188,
                "change_p": 9.0832
            },
            {
                "name": "BlackRock Advantage Small Cap Gr Instl",
                "date": "2026-09-30",
                "totalShares": 0.2553,
                "totalAssets": 0.0913,
                "currentShares": 195014,
                "change": 770,
                "change_p": 0.3964
            },
            {
                "name": "DFA US Micro Cap I",
                "date": "2026-08-31",
                "totalShares": 0.2307,
                "totalAssets": 0.0087,
                "currentShares": 176234,
                "change": 7630,
                "change_p": 4.5254
            },
            {
                "name": "Schwab Small Cap Index",
                "date": "2026-09-30",
                "totalShares": 0.2164,
                "totalAssets": 0.0084,
                "currentShares": 165280,
                "change": 23374,
                "change_p": 16.4715
            },
            {
                "name": "DFA US Small Cap I",
                "date": "2026-08-31",
                "totalShares": 0.2057,
                "totalAssets": 0.0031,
                "currentShares": 157099,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Vanguard Health Care ETF",
                "date": "2026-09-30",
                "totalShares": 0.1863,
                "totalAssets": 0.0024,
                "currentShares": 142271,
                "change": 156,
                "change_p": 0.1098
            },
            {
                "name": "Avantis US Small Cap Equity ETF",
                "date": "2026-10-29",
                "totalShares": 0.1857,
                "totalAssets": 0.0166,
                "currentShares": 141811,
                "change": 0,
                "change_p": 0
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        ]
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}
Fulcrum Therapeutics Inc

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