Stock Fundamentals

Company Information

Company Name
Insmed Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US4576693075
CIK: 0001104506
CUSIP: 457669109
Currency: USD
Full Time Employees: 1,664
Phone: 908 977 9900
Fiscal Year End: December
IPO Date: Jun 01, 2000
Description:

Insmed Incorporated develops and commercializes therapies for patients with serious and rare diseases in the United States, Europe, Japan, and internationally. The company offers ARIKAYCE for the treatment of refractory nontuberculous mycobacterial lung infections, as well as is in phase 3 clinical trial for the treatment of mycobacterium avium complex lung disease as part of a combination antibacterial drug regimen for adult patients. It also develops brensocatib, an oral reversible inhibitor of dipeptidyl peptidase 1(DPP1) that is in phase 3 clinical trial for the treatment of bronchiectasis; and in phase 2 clinical trial for the treatment of chronic rhinosinusitis without nasal polyps and hidradenitis suppurativa. In addition, the company is developing treprostinil palmitil inhalation powder, an inhaled formulation of a treprostinil prodrug treprostinil palmitil, which is in phase 3 clinical trial for the treatment of pulmonary hypertension associated with interstitial lung disease; and phase 2 clinical trial for the treatment of pulmonary arterial hypertension. Further, it develops INS1201, a microdystrophin adeno-associated virus gene replacement therapy which is in phase 1 clinical trial for the treatment of Duchenne muscular dystrophy, as well as it is also developing pre-clinical research programs for gene therapy, AI-driven protein engineering, protein manufacturing, RNA end-joining, and synthetic rescue. In addition, it provides INS1148, monoclonal antibody targeting stem cell factor called SCF248 that is in phase-2 clinical trial for the treatment of interstitial lung disease, and asthma; and INS1202, an intrathecally delivered gene therapy which is in phase 1 of clinical trial for the treatment of amyotrophic lateral sclerosis. The company was founded in 1988 and is headquartered in Bridgewater, New Jersey.

Address:

700 US Highway 202/206, Bridgewater, NJ, United States, 08807

Directors & Officers

Name Title Year Born
Mr. William H. Lewis J.D., M.B.A. President, CEO & Chairman 1969
Ms. Sara M. Bonstein M.B.A. Chief Financial Officer 1981
Mr. Roger Adsett M.B.A. Chief Operating Officer 1969
Mr. Michael Alexander Smith J.D. Chief Legal Officer & Corporate Secretary 1978
Dr. Martina Flammer M.B.A., M.D. Chief Medical Officer 1964
Mr. Brian K. Kaspar Ph.D. Chief Scientific Officer 1974
Bryan Dunn Vice President of Investor Relations NA
Ms. Christie Camelio Chief Compliance Officer NA
Ms. Claire Mulhearn Vice President of Corporate Communications NA
Ms. S. Nicole Schaeffer M.B.A. Chief People Strategy Officer 1968

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Apr 16, 2026 William Lewis N/A Sale 10.70K $143.97 $1.54M
Apr 06, 2026 William Lewis N/A Sale 10.70K $163.22 $1.75M
Apr 01, 2026 Roger Adsett N/A Sale 88.06K $164.63 $14.50M
Mar 30, 2026 Michael Alexander Smith N/A Sale 19.64K $150.98 $2.96M
Mar 19, 2026 William Lewis N/A Sale 10.70K $143.52 $1.54M
Mar 05, 2026 William Lewis N/A Sale 10.70K $146.03 $1.56M
Feb 19, 2026 William Lewis N/A Sale 10.70K $150.97 $1.62M
Feb 09, 2026 William Lewis N/A Sale 13.40K $147.79 $1.98M
Feb 03, 2026 Sara Bonstein N/A Sale 748.00 $156.34 $116.94K
Feb 03, 2026 William Lewis N/A Sale 3.01K $156.34 $470.43K
Feb 03, 2026 Roger Adsett N/A Sale 791.00 $156.17 $123.53K
Feb 03, 2026 Michael Alexander Smith N/A Sale 640.00 $156.27 $100.01K
Jan 20, 2026 William Lewis N/A Sale 10.70K $158.93 $1.70M
Jan 12, 2026 William Lewis N/A Sale 19.22K $169.00 $3.25M
Jan 08, 2026 Michael Alexander Smith N/A Sale 1.05K $174.17 $183.40K
Jan 08, 2026 Roger Adsett N/A Sale 2.06K $174.17 $358.62K
Jan 08, 2026 Sara Bonstein N/A Sale 1.45K $174.17 $252.02K
Jan 08, 2026 William Lewis N/A Sale 3.22K $174.17 $561.35K
Jan 07, 2026 Michael Alexander Smith N/A Sale 709.00 $175.07 $124.12K
Jan 07, 2026 Roger Adsett N/A Sale 802.00 $175.07 $140.41K

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
JPMorgan Chase & Co 24.15M Mar 31, 2026 11.14% $0.24 4.10%
Vanguard Group Inc 21.08M Dec 31, 2025 9.72% $0.05 5.72%
Darwin Global Management, Ltd. 16.81M Mar 31, 2026 7.75% $68.33 -19.72%
BlackRock Inc 16.68M Mar 31, 2026 7.69% $0.05 10.71%
FMR Inc 13.16M Mar 31, 2026 6.07% $0.11 32.56%
Vanguard Portfolio Management, LLC 10.37M Mar 31, 2026 4.79% $0.09 0.00%
Vanguard Capital Management, LLC 9.64M Mar 31, 2026 4.45% $0.04 0.00%
Baker Bros Advisors LP 7.42M Mar 31, 2026 3.42% $6.97 12.56%
Artisan Partners Limited Partnership 6.53M Mar 31, 2026 3.01% $1.71 34.76%
D. E. Shaw & Co LP 5.63M Mar 31, 2026 2.60% $0.55 29.30%
Capital Research & Mgmt Co - Division 3 5.60M Mar 31, 2026 2.58% $0.21 8.61%
State Street Corp 5.55M Mar 31, 2026 2.56% $0.03 6.73%
RTW INVESTMENTS, LLC 4.84M Mar 31, 2026 2.23% $7.88 0.00%
Geode Capital Management, LLC 4.45M Mar 31, 2026 2.05% $0.05 3.52%
T. Rowe Price Associates, Inc. 3.09M Mar 31, 2026 1.43% $0.06 -23.44%
Ameriprise Financial Inc 3.06M Mar 31, 2026 1.41% $0.12 55.30%
NORGES BANK 2.91M Dec 31, 2025 1.34% $0.05 50.45%
Franklin Resources Inc 2.62M Mar 31, 2026 1.21% $0.10 -5.02%
Citadel Advisors Llc 2.18M Mar 31, 2026 1.01% $0.06 88.59%
Amvescap Plc. 1.99M Mar 31, 2026 0.92% $0.05 -27.06%

Shares Statistics

Shares Outstanding: 216.75M
Shares Float: 198.30M
% Insiders: 51.70%
% Institutions: 10,364.50%
Short % Float: 8.34%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 JPMorgan Large Cap Growth I 10.63M 4.91% ▲ 0.00% Apr 30, 2026
2 Vanguard Total Stock Mkt Idx Inv 6.87M 3.17% ▲ 0.25% Apr 30, 2026
3 Capital Group Growth Fnd of Amer Comp 5.10M 2.35% ▲ 48.12% Mar 31, 2026
4 American Funds Growth Fund of Amer A 5.10M 2.35% ▲ 48.12% Mar 31, 2026
5 Invesco QQQ Trust 4.68M 2.16% ▲ 0.47% May 29, 2026
6 Vanguard Small Cap Index 2.48M 1.15% ▼ 0.22% Apr 30, 2026
7 Vanguard Institutional Extnd Mkt Idx Tr 2.41M 1.11% ▲ 1.02% Apr 30, 2026
8 JPMCB Large Cap Growth CF-A 2.36M 1.09% ▲ 13.32% Mar 31, 2026
9 Vanguard Mid Cap Index Institutional 2.33M 1.08% ▲ 0.22% Apr 30, 2026
10 iShares Biotechnology ETF 1.57M 0.72% ▲ 1.46% May 29, 2026

Valuation Metrics

Enterprise Value: $24.42B
Trailing P/E: 0.00
Forward P/E: 16.37

Financial Highlights

Market Cap: $25.06B
EBITDA: $-949.04M
PEG Ratio: $1.09
Book Value: $3.26
Earnings/Share: $-5.76
Profit Margin: -144.44%
Operating Margin: -65.46%
ROA (TTM): -31.11%
ROE (TTM): -294.46%
Revenue (TTM): $819.56M
Revenue/Share (TTM): $3.95
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 229.60%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 3.83x 0.76x 0.67x -14.04x -0.48x
2024-12-31 5.45x 3.92x 0.86x -10.34x -1.37x
2023-12-31 4.12x -3.51x 1.25x -8.69x -1.77x
2022-12-31 6.69x 12.89x 0.95x -17.29x -2.53x
2021-12-31 6.19x 1.41x 0.67x -9.27x -1.50x
2020-12-31 5.24x 1.34x 0.65x -8.97x -1.47x
2019-12-31 6.51x 1.33x 0.65x -8.49x -1.60x
2018-12-31 6.51x 1.52x 0.66x -12.07x -1.07x
2017-12-31 8.72x 0.31x 0.22x -31.89x -0.60x
2016-12-31 6.02x 0.71x 0.35x -49.57x -0.64x
2015-12-31 12.94x 0.08x 0.13x -40.67x -0.22x
2014-12-31 8.39x 0.27x 0.19x -36.18x -0.58x
2013-12-31 7.06x 0.14x 0.19x -22.81x -0.36x
2012-12-31 5.94x 0.16x 0.21x -55.62x -0.48x
2011-12-31 17.29x 0.00x 0.04x -6,171.90x 0.00x
2010-12-31 32.58x 0.00x 0.02x -74.24x -0.03x
2009-12-31 44.81x 0.00x 0.02x -11.11x 0.00x
2008-12-31 0.53x -0.74x 1.59x -11.47x -0.16x
2007-12-31 4.61x 0.29x 0.41x -29.97x -0.17x
2006-12-31 2.63x 0.23x 0.51x -14.68x -0.06x
2005-12-31 3.94x 0.61x 0.54x -1.93x -0.44x
2004-12-31 1.92x 0.00x 0.44x N/A 0.00x
2003-12-31 10.10x 0.00x 0.12x N/A 0.00x
2002-12-31 7.23x 0.10x 0.17x N/A -0.07x
2001-12-31 5.37x 0.08x 0.17x N/A -0.13x
2000-12-31 20.45x 0.00x 0.06x N/A 0.00x
1999-12-31 5.61x 0.00x 0.16x N/A 0.00x

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