MDGL

Madrigal Pharmaceuticals Inc

MDGL.US madrigalpharma.com
533.12
-13.54 (-2.48%)
USD · NASDAQ
52-week range
393.61
615.00
Trading at 63% of the 52-week range
Market Cap
12.34B
P/E Ratio
0.00
Forward P/E
81.97
Book Value
22.68
Div. Yield
N/A
% Institutions
104.52%
% Insiders
5.88%

1 Year

+23.9%

3 Year

+188.2%

10 Year

+4,805.3%
Description

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.

Company Information

Company Name
Madrigal Pharmaceuticals Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US5588681057
CIK: 0001157601
CUSIP: 87162T206
Currency: USD
Full Time Employees: 915
Phone: 267 824 2827
Fiscal Year End: December
IPO Date: Feb 06, 2007
Description:

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.

Address:

1001 Conshohocken State Road, West Conshohocken, PA, United States, 19428

People

Directors & Officers

Name Title Year Born
Mr. William J. Sibold CEO, President & Director 1966
Dr. Rebecca A. Taub M.D. Founder, Senior Scientific & Medical Advisor and Director 1952
Ms. Mardi C. Dier Executive VP & CFO 1964
Ms. Shannon Kelley Executive VP, Chief Legal Officer & Corporate Secretary 1975
Ms. Carole Huntsman Executive VP & Chief Commercial Officer 1965
Dr. David Soergel M.D. Executive VP & Chief Medical Officer 1968
Mr. Mark Underwood Executive Vice President of Business Planning & Operations NA
Ms. Rita Thakkar Senior VP & Chief Accounting Officer 1974
Mr. Ronald Filippo Executive VP & Chief Information Officer NA
Ms. Tina E. Ventura Chief Investor Relations Officer NA

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Mar 06, 2026 Mardi Dier N/A Sale 1.98K $430.87 $853.98K
Mar 06, 2026 Carole Huntsman N/A Sale 419.00 $431.94 $180.98K
Mar 06, 2026 William John Sibold N/A Sale 1.66K $431.94 $718.32K
Mar 06, 2026 Rebecca Taub N/A Sale 491.00 $431.94 $212.08K
Mar 06, 2026 Shannon T Kelley N/A Sale 360.00 $431.94 $155.50K
Mar 02, 2026 Mardi Dier N/A Sale 1.18K $427.21 $505.39K
Jan 26, 2026 Carole Huntsman N/A Sale 910.00 $493.78 $449.34K
Jan 26, 2026 Rebecca Taub N/A Sale 647.00 $492.42 $318.60K
Jan 26, 2026 William John Sibold N/A Sale 1.58K $492.42 $776.55K
Jan 20, 2026 Rebecca Taub N/A Sale 2.24K $490.77 $1.10M
Jan 20, 2026 Shannon T Kelley N/A Sale 692.00 $497.36 $344.17K
Jan 09, 2026 Paul A Friedman N/A Sale 24.52K $522.39 $12.81M
Jan 09, 2026 Rebecca Taub N/A Sale 18.41K $522.40 $9.62M
Jan 09, 2026 Rebecca Taub N/A Sale 240.00 $550.33 $132.08K
Jan 09, 2026 Paul A Friedman N/A Sale 280.00 $551.24 $154.35K
Dec 10, 2025 Paul A Friedman N/A Sale 24.80K $552.18 $13.69M
Dec 10, 2025 Rebecca Taub N/A Sale 18.65K $552.15 $10.30M
Dec 04, 2025 William John Sibold N/A Sale 2.40K $575.34 $1.38M
Dec 02, 2025 Mardi Dier N/A Sale 4.17K $578.34 $2.41M
Nov 21, 2025 Carole Huntsman N/A Sale 1.96K $553.11 $1.08M

Shareholders

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
Baker Bros Advisors LP 2.14M Mar 31, 2026 9.27% $6.44 0.00%
HHG PLC 2.02M Mar 31, 2026 8.74% $0.50 27.37%
RTW INVESTMENTS, LLC 1.99M Mar 31, 2026 8.63% $10.38 0.00%
venBio Select Advisor LLC 1.82M Mar 31, 2026 7.87% $9.36 0.59%
BlackRock Inc 1.56M Mar 31, 2026 6.75% $0.01 -5.15%
Paulson & Company Inc 1.34M Jun 30, 2026 5.80% $27.94 -3.75%
Vanguard Portfolio Management, LLC 841.15K Mar 31, 2026 3.64% $0.02 0.00%
Vanguard Capital Management, LLC 827.14K Mar 31, 2026 3.58% $0.01 0.00%
Wellington Management Company LLP 825.71K Jun 30, 2026 3.57% $0.08 18.81%
State Street Corp 609.53K Mar 31, 2026 2.64% $0.01 4.55%
FMR Inc 511.73K Mar 31, 2026 2.21% $0.01 16.46%
Geode Capital Management, LLC 455.87K Mar 31, 2026 1.97% $0.01 0.91%
Citadel Advisors Llc 453.84K Mar 31, 2026 1.96% $0.04 1,156.00%
Amvescap Plc. 329.52K Mar 31, 2026 1.43% $0.02 -9.80%
T. Rowe Price Associates, Inc. 328.11K Mar 31, 2026 1.42% $0.02 4.61%
William Blair Investment Management, LLC 324.12K Jun 30, 2026 1.40% $0.52 -4.82%
Polar Capital Holdings PLC 289.31K Mar 31, 2026 1.25% $0.54 7.09%
The Goldman Sachs Group Inc 277.37K Mar 31, 2026 1.20% $0.02 -9.31%
Armistice Capital, LLC 264.58K Mar 31, 2026 1.15% $2.46 -0.42%
Hood River Capital Management LLC 249.51K Mar 31, 2026 1.08% $1.31 0.79%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 Vanguard MStar Total Stk Mkt Idx Invest 586.88K 2.54% ▲ 0.30% Jul 31, 2026
2 Vanguard Health Care Inv 521.93K 2.26% ▲ 17.51% Jun 30, 2026
3 Vanguard Small Cap Index 424.12K 1.84% ▲ 0.26% Jul 31, 2026
4 Janus Concentrated Growth CF 338.60K 1.47% ▼ 21.15% Jun 30, 2026
5 Janus Henderson Forty S 338.60K 1.47% ▲ 0.00% Aug 31, 2026
6 Polar Capital Biotech S Inc 273.99K 1.19% ▲ 18.60% Jul 31, 2026
7 Vanguard MStar Small Cap Growth Indx Inv 245.51K 1.06% ▲ 0.48% Jul 31, 2026
8 Janus Henderson Enterprise D 233.27K 1.01% ▲ 0.00% Aug 31, 2026
9 Janus Henderson Mid Cap Growth MA 233.27K 1.01% ▲ 0.00% Jun 30, 2026
10 Janus Inst Mid Cap Growth CF 233.27K 1.01% ▲ 0.00% Jun 30, 2026

Financial Highlights

Market Cap: $12.34B
EBITDA: $-321.10M
PEG Ratio: $0.00
Book Value: $22.68
Earnings/Share: $-14.01
Profit Margin: -25.32%
Operating Margin: -15.46%
ROA (TTM): -17.84%
ROE (TTM): -53.31%
Revenue (TTM): $1.28B
Revenue/Share (TTM): $56.15
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 71.20%

Valuation Metrics

Enterprise Value: $12.01B
Trailing P/E: 0.00
Forward P/E: 81.97

Shares Statistics

Shares Outstanding: 23.10M
Shares Float: 13.72M
% Insiders: 5.88%
% Institutions: 104.52%
Short % Float: 10.30%

Stock Price History

1 Year Price History

3 Years Price History

10 Years Price History

Financial Charts

Revenue, Net Income & Operating Cash Flow (Yearly)

Revenue, Net Income & Operating Cash Flow (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

Open full waterfall
Line Item
Step Type
Value
Revenue
adjust
$958.40M
Cost of Goods Sold
adjust
$-56.15M
Gross Profit
subtotal
$902.26M
SG&A
adjust
$-813.83M
R&D
adjust
$-388.53M
Operating Income
subtotal
$-300.10M
Other / Non-Operating Items
adjust
$11.81M
Net Income
subtotal
$-288.28M

Earnings Per Share (EPS) History

Financial Ratios

📦 Raw API Data (JSON Explorer)

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