Stock Fundamentals

Company Information

Company Name
Opko Health Inc
Sector
Healthcare
Industry
Diagnostics & Research
Exchange
NASDAQ
ISIN: US68375N1037
CIK: 0000944809
CUSIP: 23282G105
Currency: USD
Full Time Employees: 2,275
Phone: 305 575 4100
Fiscal Year End: December
IPO Date: Nov 02, 1995
Description:

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida.

Address:

4400 Biscayne Boulevard, Miami, FL, United States, 33137

Directors & Officers

Name Title Year Born
Dr. Phillip Frost M.D., Ph.D. Chairman of the Board & CEO 1936
Dr. Jane H. Hsiao M.B.A., Ph.D. Vice Chairman of the Board & Chief Technical Officer 1947
Dr. Elias Adam Zerhouni M.D. President & Vice Chairman of the Board 1951
Mr. Adam E. Logal Senior VP, CFO, Chief Accounting Officer & Treasurer 1978
Mr. Steven D. Rubin Esq., J.D. Executive VP of Administration & Director 1960
Dr. Akhtar Ashfaq FACP, FASN, M.D. Senior Vice President of Clinical Research & Development and Medical Affairs - Opko Renal NA
Dr. Gary J. Nabel M.D., Ph.D. Chief Innovation Officer & Director 1954
Mr. Giovanni Abbadessa M.D., Ph.D. Chief Medical Officer of ModeX NA
Dr. John R. Mascola M.D. Chief Scientific Officer of ModeX NA
Dr. Charles W. Bishop Ph.D. Chief Executive Officer of OPKO Renal 1952

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Mar 20, 2026 John A Paganelli N/A Purchase 10.00K $1.14 $11.40K
Nov 21, 2025 Phillip Md Et Al Frost N/A Purchase 580.00K $1.33 $771.40K
Nov 19, 2025 Phillip Md Et Al Frost N/A Purchase 580.00K $1.31 $759.80K
Nov 18, 2025 Phillip Md Et Al Frost N/A Purchase 533.30K $1.27 $677.29K
Oct 31, 2025 Phillip Md Et Al Frost N/A Purchase 150.00K $1.42 $213.00K
Aug 08, 2025 Phillip Md Et Al Frost N/A Purchase 675.00K $1.32 $891.00K

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
Rubric Capital Management LP 47.79M Mar 31, 2026 6.33% $0.58 0.00%
BlackRock Inc 36.23M Mar 31, 2026 4.80% $0.00 3.96%
Vanguard Group Inc 32.46M Dec 31, 2025 4.30% $0.00 -13.53%
Vanguard Portfolio Management, LLC 14.77M Mar 31, 2026 1.96% $0.00 0.00%
Vanguard Capital Management, LLC 14.50M Mar 31, 2026 1.92% $0.00 0.00%
Geode Capital Management, LLC 11.30M Mar 31, 2026 1.50% $0.00 2.17%
State Street Corp 9.50M Mar 31, 2026 1.26% $0.00 6.14%
The Goldman Sachs Group Inc 7.68M Mar 31, 2026 1.02% $0.00 28.20%
UBS Group AG 6.07M Mar 31, 2026 0.80% $0.00 13.43%
Whitefort Capital Management, LP. 4.25M Mar 31, 2026 0.56% $1.43 0.00%
Northern Trust Corp 3.62M Mar 31, 2026 0.48% $0.00 5.27%
Charles Schwab Investment Management Inc 3.57M Mar 31, 2026 0.47% $0.00 -3.21%
Vanguard Fiduciary Trust Co 2.74M Mar 31, 2026 0.36% $0.00 0.00%
Awm Investment Company Inc 2.10M Mar 31, 2026 0.28% $0.27 0.00%
Citadel Advisors Llc 2.08M Mar 31, 2026 0.28% $0.00 -27.22%
Dimensional Fund Advisors, Inc. 1.56M Mar 31, 2026 0.21% $0.00 -3.18%
WASHINGTON GROWTH STRATEGIES LLC 1.36M Mar 31, 2026 0.18% $1.01 0.00%
Y.D. More Investments Ltd 1.30M Mar 31, 2026 0.17% $0.06 -0.53%
Bank of New York Mellon Corp 1.28M Mar 31, 2026 0.17% $0.00 -2.29%
Morgan Stanley - Brokerage Accounts 1.20M Mar 31, 2026 0.16% $0.00 30.38%

Shares Statistics

Shares Outstanding: 755.09M
Shares Float: 332.82M
% Insiders: 4,994.90%
% Institutions: 2,700.80%
Short % Float: 7.70%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 iShares Russell 2000 ETF 9.82M 1.30% ▲ 0.93% May 29, 2026
2 Vanguard Total Stock Mkt Idx Inv 9.43M 1.25% ▲ 0.00% Apr 30, 2026
3 Vanguard Small Cap Index 7.07M 0.94% ▲ 1.46% Apr 30, 2026
4 Vanguard Institutional Extnd Mkt Idx Tr 4.78M 0.63% ▲ 0.93% Apr 30, 2026
5 Fidelity Small Cap Index 4.00M 0.53% ▲ 0.08% Mar 31, 2026
6 iShares Russell 2000 Value ETF 3.50M 0.46% ▲ 0.00% May 29, 2026
7 iShares Biotechnology ETF 2.89M 0.38% ▲ 1.95% May 29, 2026
8 Russell 2000 Equity Index Fund B 2.64M 0.35% ▲ 11.51% Dec 31, 2025
9 Fidelity Extended Market Index 2.39M 0.32% ▼ 0.36% Apr 30, 2026
10 Vanguard Small Cap Value Index Inv 2.23M 0.30% ▼ 0.03% Apr 30, 2026

Valuation Metrics

Enterprise Value: $1.07B
Trailing P/E: 0.00
Forward P/E: 53.76

Financial Highlights

Market Cap: $1.02B
EBITDA: $-112.49M
PEG Ratio: $93.65
Book Value: $1.60
Earnings/Share: $-0.27
Profit Margin: -36.64%
Operating Margin: -41.08%
ROA (TTM): -6.36%
ROE (TTM): -16.92%
Revenue (TTM): $581.12M
Revenue/Share (TTM): $0.75
Earnings Growth (YOY): -12.60%
Revenue Growth (YOY): -17.20%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 3.97x 0.28x 0.34x -2.02x -8.63x
2024-12-31 3.43x 0.33x 0.38x -3.20x 3.34x
2023-12-31 1.55x 0.19x 0.31x -11.63x -4.05x
2022-12-31 1.85x 0.17x 0.28x -18.77x -1.00x
2021-12-31 2.49x 0.13x 0.30x 0.99x 2.59x
2020-12-31 1.39x 0.16x 0.32x 2.63x 1.68x
2019-12-31 1.30x 0.18x 0.30x -12.74x -1.50x
2018-12-31 1.24x 0.12x 0.27x -14.40x -3.05x
2017-12-31 1.12x 0.08x 0.29x -41.88x -0.92x
2016-12-31 1.84x 0.05x 0.24x -9.86x 13.67x
2015-12-31 1.80x 0.06x 0.29x -11.70x -2.07x
2014-12-31 1.72x 0.18x 0.34x -11.89x -1.13x
2013-12-31 2.64x 0.26x 0.37x -5.77x -3.03x
2012-12-31 1.50x 0.11x 0.30x -26.53x -0.89x
2011-12-31 5.30x 0.05x 0.30x -23.07x -0.45x
2010-12-31 2.08x 0.64x 0.70x -9.17x -1.72x
2009-12-31 4.90x 0.28x 0.34x N/A -0.71x
2008-12-31 1.75x 33.33x 0.98x N/A -0.34x
2007-12-31 3.00x 0.85x 0.58x N/A -0.60x
2006-12-31 12.99x 0.00x 0.08x N/A 0.00x
2005-12-31 32.49x 0.00x 0.03x -719.00x 0.00x
2004-12-31 42.13x 0.00x 0.02x -1,025.50x 0.00x
2003-12-31 10.92x 0.00x 0.09x -1,866.00x 0.00x
2002-12-31 12.95x 0.01x 0.08x N/A -0.02x
2001-12-31 20.16x 0.01x 0.05x N/A -0.02x
2000-12-31 42.09x 0.00x 0.04x -956.00x -0.02x
1999-12-31 3.27x 0.05x 0.42x N/A -0.03x
1998-12-31 9.86x 0.03x 0.21x N/A -0.07x
1997-12-31 3.17x 0.09x 0.61x N/A -0.03x
1996-12-31 7.25x 0.00x 0.41x N/A 0.00x
1995-12-31 3.60x 0.00x 0.23x N/A 0.00x

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