SYRS
Syros Pharmaceuticals Inc

SYRS.US syros.com
Healthcare · Biotechnology
0.00
+0.00 (+0.00%)
USD · PINK
52-week range
0.00
0.01
Trading at 4% of the 52-week range
Market Cap
10.73K
P/E Ratio
0.00
Forward P/E
0.00
Book Value
-0.42
Div. Yield
N/A
% Institutions
9.62%
% Insiders
0.075%
1 Year

-75.0%
3 Year

-100.0%
10 Year

-100.0%
Description
Syros Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development of treatment for hematologic malignancies. The company's lead product candidates are Tamibarotene, a selective retinoic acid receptor alpha agonist, which is in Phase III clinical trial for genomically defined subset of patients with myelodysplastic syndrome and Phase II clinical trial for patients with acute myeloid leukemia; SY-2101, a novel oral form of arsenic trioxide for treating patients with acute promyelocytic leukemia; and SY-5609, a cyclin-dependent kinase 7 inhibitor, which is in a Phase I clinical trial in patients with select advanced solid tumors. The company was formerly known as LS22, Inc. and changed its name to Syros Pharmaceuticals, Inc. in August 2012. Syros Pharmaceuticals, Inc. was incorporated in 2011 and is headquartered in Cambridge, Massachusetts.
People

▼
Directors & Officers

Name	Title	Year Born
Dr. James E. Bradner M.D.	Founder	1972
Dr. Nathanael S. Gray Ph.D.	Scientific Founder & Member of Scientific Advisory Board	NA
Matthew Foster	Chief Restructuring Officer	NA
Insider Trading

Date	Insider Name	Title	Transaction Type	Shares	Price	Value
Dec 02, 2024	Nancy A Simonian	N/A	Sale	37.07K	$0.27	$10.01K
Nov 25, 2024	Nancy A Simonian	N/A	Sale	134.71K	$0.27	$36.37K
Sep 12, 2024	Jason Haas	N/A	Purchase	45.34K	$1.68	$76.18K
Sep 10, 2024	Conley Chee	N/A	Purchase	50.00K	$1.51	$75.50K
Sep 10, 2024	Jason Haas	N/A	Purchase	35.36K	$1.55	$54.81K
Jun 28, 2024	Richard A Young	N/A	Sale	34.84K	$5.12	$178.37K
Apr 02, 2024	David Roth	N/A	Sale	150.00	$4.98	$747.00
Shareholders

▼
Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
Bain Capital Life Sciences Investors, LLC	2.75M	Dec 31, 2024	10.25%	$0.07	0.00%
BlackRock Inc	277.25K	Dec 31, 2024	1.03%	$0.00	5.99%
Vanguard Group Inc	268.15K	Dec 31, 2024	1.00%	$0.00	-71.87%
Omega Fund Management LLC	251.27K	Dec 31, 2024	0.94%	$0.05	0.00%
Geode Capital Management, LLC	196.25K	Dec 31, 2024	0.73%	$0.00	-4.12%
Affinity Asset Advisors, LLC	150.00K	Dec 31, 2024	0.56%	$0.00	0.00%
Citigroup Inc	139.22K	Dec 31, 2024	0.52%	$0.00	20,165.50%
Qube Research & Technologies	122.17K	Dec 31, 2024	0.46%	$0.00	57.21%
TWO SIGMA SECURITIES, LLC	107.74K	Dec 31, 2024	0.40%	$0.00	0.00%
Renaissance Technologies Corp	96.04K	Dec 31, 2024	0.36%	$0.00	-0.41%
HRT FINANCIAL LLC	87.54K	Dec 31, 2024	0.33%	$0.00	0.00%
XTX Topco Ltd	81.46K	Dec 31, 2024	0.30%	$0.00	182.51%
State Street Corp	69.43K	Dec 31, 2024	0.26%	$0.00	0.00%
Jane Street Group LLC	52.92K	Dec 31, 2024	0.20%	$0.00	0.00%
Two Sigma Investments LLC	48.86K	Dec 31, 2024	0.18%	$0.00	71.59%
UBS Group AG	45.05K	Dec 31, 2024	0.17%	$0.00	169.31%
Northern Trust Corp	40.81K	Dec 31, 2024	0.15%	$0.00	0.00%
1492 Capital Management, LLC	39.24K	Dec 31, 2024	0.15%	$0.00	0.00%
Virtu Financial LLC	32.79K	Dec 31, 2024	0.12%	$0.00	67.05%
Baader Bank INC	22.09K	Dec 31, 2024	0.08%	$0.00	0.00%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Vanguard Institutional Extnd Mkt Idx Tr	257.64K	0.96%	▲ 0.00%	Jan 31, 2025
2	Fidelity Extended Market Index	97.61K	0.36%	▼ 1.08%	Jan 31, 2025
3	iShares Micro-Cap ETF	45.83K	0.17%	▲ 0.00%	Feb 28, 2025
4	Extended Equity Market Fund K	44.75K	0.17%	▼ 1.36%	Dec 31, 2024
5	Fidelity Total Market Index	39.83K	0.15%	▲ 0.00%	Jan 31, 2025
6	Fidelity Series Total Market Index	23.73K	0.09%	▲ 0.00%	Jan 31, 2025
7	Northern Trust Extended Eq Market Idx	22.60K	0.08%	▲ 0.00%	Dec 31, 2024
8	NT Ext Equity Mkt Idx Fd - L	22.60K	0.08%	▲ 0.00%	Dec 31, 2024
9	NT Ext Equity Mkt Idx Fd - NL	16.81K	0.06%	▲ 0.00%	Dec 31, 2024
10	NT Ext Equity Mkt Idx Fd - DC - NL - T2	13.33K	0.05%	▼ 1.62%	Dec 31, 2024
Financial Highlights

▼
Market Cap: $10.73K
EBITDA: $-110.18M
PEG Ratio: $0.00
Book Value: $-0.42
Earnings/Share: $-3.07
Profit Margin: 0.00%
Operating Margin: -28,891.71%
ROA (TTM): -59.88%
ROE (TTM): -776.96%
Revenue (TTM): $386.00K
Revenue/Share (TTM): $0.01
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): -3.30%
Valuation Metrics

Enterprise Value: $1.96M
Trailing P/E: 0.00
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 26.83M
Shares Float: 26.83M
% Insiders: 0.075%
% Institutions: 9.62%
Short % Float: 3.81%
Stock Price History

▼
1 Year Price History

3 Years Price History

10 Years Price History

Financial Charts

▼
Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Revenue, Net Income & Operating Cash Flow (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$9.94M
Cost of Goods Sold
adjust
$-2.25M
Gross Profit
subtotal
$7.68M
SG&A
adjust
$-28.28M
R&D
adjust
$-108.15M
Operating Income
subtotal
$-128.99M
Other / Non-Operating Items
adjust
$-35.59M
Net Income
subtotal
$-164.57M
Earnings Per Share (EPS) History

▼
Financial Ratios

▼
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
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        "Code": "SYRS",
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}
Syros Pharmaceuticals Inc

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