Stock Fundamentals

Company Information

Company Name
Twist Bioscience Corp
Sector
Healthcare
Industry
Diagnostics & Research
Exchange
NASDAQ
ISIN: US90184D1000
CIK: 0001581280
CUSIP: 90184D100
Currency: USD
Full Time Employees: 979
Phone: 800 719 0671
Fiscal Year End: September
IPO Date: Oct 31, 2018
Description:

Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. The company offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage, and various applications within academic research by biotech, pharma, industrial chemical, and agricultural companies, as well as academic labs; Oligo pools used in targeted NGS, CRISPR gene editing, mutagenesis experiments, DNA origami, DNA computing, data storage in DNA, and other applications; and immunoglobulin G proteins for customers focused on the pursuit of drug discovery and development. It also provides NGS tools comprising library preparation kits, human exome kits, and fixed and custom panels, as well as alliance panels used within diagnostic tests for various indications, population genetics research and biomarker discovery, translational research, microbiology, and applied markets research; and methylation detection kits for cancer, and rare and inherited disease study, as well as fast hybridization and full RNA sequencing workflow solution. In addition, it offers synthetic SARS-CoV-2 RNA reference sequences as positive controls to develop both NGS and reverse transcription-polymerase chain reaction assays; synthetic monkeypox controls; and various respiratory viral controls, including for influenzas, respiratory syncytial virus, rhinoviruses, SARS, MERS, and coronaviruses. Further, it offers SARS-CoV-2 Research Panels, such as the Twist Respiratory Virus Panel and the Pan-Viral Research Panel, for the detection of disease in a research setting; precision DNA libraries for antibody engineering, affinity maturation, and humanization; and antibody optimization solution to enable simultaneous optimization of multiple characteristics of a given antibody. The company has a strategic collaboration with bitBiome Inc. The company was incorporated in 2013 and is headquartered in South San Francisco, California.

Address:

681 Gateway Boulevard, South San Francisco, CA, United States, 94080

Directors & Officers

Name Title Year Born
Dr. Emily Marine Leproust Ph.D. Co-Founder, Board Chair & CEO 1973
Dr. Patrick John Finn Ph.D. President & COO 1972
Mr. Adam Laponis Chief Financial Officer 1977
Mr. Dennis Cho J.D. Chief Legal Officer & Corporate Secretary 1971
Ms. Paula Green Senior Vice President of Human Resources 1968
Mr. Robert F. Werner VP & Chief Accounting Officer 1973
Mr. Siyuan Chen Chief Technology Officer NA
Dr. Michael Fero Ph.D. Chief Information Officer NA
Dr. Colby Souders Ph.D. Chief Scientific Officer NA
Ms. Nicole Moreno Senior Vice President of Sales & Support NA

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Apr 22, 2026 Emily M Leproust N/A Sale 8.06K $65.29 $526.30K
Apr 21, 2026 Emily M Leproust N/A Sale 1.61K $65.01 $104.67K
Apr 17, 2026 Adam Laponis N/A Sale 4.00K $60.00 $240.00K
Apr 14, 2026 Adam Laponis N/A Sale 3.00K $55.00 $165.00K
Apr 09, 2026 Adam Laponis N/A Sale 2.60K $49.89 $129.56K
Apr 01, 2026 Melissa A Starovasnik N/A Sale 1.00K $51.00 $51.00K
Mar 17, 2026 Robert Chess N/A Sale 10.00K $47.00 $470.00K
Mar 06, 2026 Dennis Cho N/A Sale 425.00 $46.43 $19.73K
Mar 06, 2026 Emily M Leproust N/A Sale 2.42K $46.43 $112.50K
Mar 06, 2026 Paula Green N/A Sale 935.00 $46.43 $43.41K
Feb 12, 2026 Adam Laponis N/A Sale 7.00K $50.00 $350.00K
Feb 11, 2026 Dennis Cho N/A Sale 5.00K $49.93 $249.65K
Feb 06, 2026 Jan Johannessen N/A Sale 2.20K $47.91 $105.40K
Feb 04, 2026 Robert F Werner N/A Sale 7.00K $45.65 $319.55K
Feb 03, 2026 Dennis Cho N/A Sale 1.10K $46.58 $51.19K
Feb 03, 2026 Emily M Leproust N/A Sale 5.00K $46.58 $232.95K
Feb 03, 2026 Paula Green N/A Sale 1.19K $46.58 $55.62K
Feb 03, 2026 Robert F Werner N/A Sale 175.00 $46.58 $8.15K
Jan 13, 2026 Adam Laponis N/A Sale 3.00K $40.00 $120.00K
Jan 09, 2026 Adam Laponis N/A Sale 2.74K $35.26 $96.54K

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
Artisan Partners Limited Partnership 6.37M Mar 31, 2026 10.23% $0.49 9.22%
ARK Investment Management LLC 6.34M Mar 31, 2026 10.19% $2.34 -16.10%
Vanguard Group Inc 5.78M Dec 31, 2025 9.28% $0.00 0.14%
BlackRock Inc 5.55M Mar 31, 2026 8.92% $0.00 -5.78%
EdgePoint Investment 5.38M Mar 31, 2026 8.64% $2.05 0.08%
William Blair Investment Management, LLC 5.27M Mar 31, 2026 8.46% $0.83 -11.50%
State Street Corp 3.67M Mar 31, 2026 5.89% $0.01 1.18%
Vanguard Portfolio Management, LLC 2.65M Mar 31, 2026 4.25% $0.01 0.00%
Vanguard Capital Management, LLC 2.64M Mar 31, 2026 4.24% $0.00 0.00%
Amvescap Plc. 2.17M Mar 31, 2026 3.49% $0.02 68.33%
FMR Inc 1.89M Mar 31, 2026 3.04% $0.00 2,641.55%
The Goldman Sachs Group Inc 1.71M Mar 31, 2026 2.74% $0.01 0.53%
Geode Capital Management, LLC 1.52M Mar 31, 2026 2.44% $0.00 4.14%
Amova Asset Management Americas, Inc 1.50M Mar 31, 2026 2.40% $1.01 -21.38%
Sumitomo Mitsui Trust Group Inc 1.50M Mar 31, 2026 2.40% $0.05 -21.38%
Farallon Capital Management, L.L.C. 1.43M Mar 31, 2026 2.29% $0.39 18,562.09%
Thrivent Financial For Lutherans 1.31M Mar 31, 2026 2.11% $0.12 -3.59%
Soleus Capital Management, L.P. 1.23M Mar 31, 2026 1.97% $2.36 -34.12%
Citadel Advisors Llc 1.22M Mar 31, 2026 1.96% $0.01 3,707.92%
Baillie Gifford & Co Limited. 1.22M Mar 31, 2026 1.95% $0.06 -4.78%

Shares Statistics

Shares Outstanding: 62.27M
Shares Float: 55.37M
% Insiders: 120.00%
% Institutions: 12,431.90%
Short % Float: 28.74%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 ARK Disruptive Innovation Full Composite 3.55M 5.70% ▼ 19.60% Mar 31, 2026
2 ARK Innovation ETF 3.26M 5.23% ▲ 2.25% May 31, 2026
3 EdgePoint Global 2.15M 3.45% ▲ 64.12% Sep 30, 2025
4 EdgePoint Global Portfolio Series F 2.15M 3.45% ▲ 64.12% Sep 30, 2025
5 State Street® SPDR® S&P® Biotech ETF 2.00M 3.21% ▼ 0.61% May 31, 2026
6 ARK Genomic Revolution 1.96M 3.14% ▼ 8.73% Mar 31, 2026
7 Vanguard Total Stock Mkt Idx Inv 1.85M 2.98% ▲ 0.31% Apr 30, 2026
8 ARK Genomic Revolution ETF 1.67M 2.68% ▼ 0.26% May 31, 2026
9 iShares Russell 2000 ETF 1.45M 2.33% ▲ 0.93% May 29, 2026
10 Vanguard Small Cap Index 1.34M 2.15% ▼ 0.21% Apr 30, 2026

Valuation Metrics

Enterprise Value: $5.76B
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $5.83B
EBITDA: $-109.84M
Book Value: $7.32
Earnings/Share: $-1.28
Profit Margin: -19.85%
Operating Margin: -34.92%
ROA (TTM): -12.94%
ROE (TTM): -18.16%
Revenue (TTM): $409.48M
Revenue/Share (TTM): $6.74
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 19.30%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-09-30 3.64x 0.03x 0.26x N/A -0.27x
2024-09-30 4.88x 0.03x 0.23x -7,614.86x -0.08x
2023-09-30 5.79x 0.02x 0.20x -43,431.80x -0.09x
2022-09-30 6.58x 0.02x 0.18x -3,112.76x -0.06x
2021-09-30 8.67x 0.02x 0.17x -416.15x -0.07x
2020-09-30 9.29x 0.03x 0.16x -177.99x -0.08x
2019-09-30 5.28x 0.05x 0.19x -84.12x -0.08x
2018-09-30 5.16x -0.05x 2.74x -53.74x -0.15x
2017-09-30 7.16x -0.14x 2.56x -64.62x -0.34x
2016-09-30 6.80x -0.15x 2.00x -58.52x -0.29x

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