TSHA.US Fundamentals - AlphaKey Financial

People

▼
Directors & Officers

Name	Title	Year Born
Mr. Sean P. Nolan	CEO & Chairman	1968
Dr. Sukumar Nagendran M.D.	President, Head of Research & Development and Director	1967
Mr. Kamran Alam CPA, M.B.A.	CFO & Corporate Secretary	1978
Hayleigh Collins	Director of Corporate Communications & Investor Relations	NA
Mr. Michael B. Johannesen	Chief Legal Officer & Corporate Secretary	1966
Mr. Frederick Porter Ph.D.	Chief of Staff & Technical Operations Officer	NA
Ms. Emily McGinnis M.P.H.	Chief Patient & External Affairs Officer	NA
Mr. Sean McAuliffe	Chief Business Officer	NA
Dr. Steven Gray Ph.D.	Chief Scientific Advisor of UT Southwestern Gene Therapy Program	NA
Berge Minassian M.D.	Chief Medical Advisor of UT Southwestern Gene Therapy Program	NA
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Apr 10, 2026	Sukumar Nagendran	N/A	Sale	200.00K	$4.46	$892.00K	SEC
Feb 04, 2026	Kamran Alam	N/A	Sale	1.66K	$4.52	$7.48K	SEC
Jan 26, 2026	Kamran Alam	N/A	Sale	23.85K	$4.61	$109.94K	SEC
Jan 26, 2026	Sean P Nolan	N/A	Sale	41.31K	$4.61	$190.45K	SEC
Jan 26, 2026	Sukumar Nagendran	N/A	Sale	26.92K	$4.61	$124.09K	SEC
Jan 23, 2026	Kamran Alam	N/A	Sale	78.97K	$4.75	$375.10K	SEC
Jan 23, 2026	Sean P Nolan	N/A	Sale	136.79K	$4.75	$649.75K	SEC
Jan 23, 2026	Sukumar Nagendran	N/A	Sale	89.13K	$4.75	$423.38K	SEC
Jan 12, 2026	Sukumar Nagendran	N/A	Sale	200.00K	$4.71	$942.00K	SEC
Dec 01, 2025	Sukumar Nagendran	N/A	Sale	260.05K	$4.51	$1.17M	SEC
Nov 28, 2025	Sukumar Nagendran	N/A	Sale	110.13K	$4.75	$523.09K	SEC
Sep 10, 2025	Sukumar Nagendran	N/A	Sale	200.00K	$3.23	$646.00K	SEC
May 30, 2025	Paul B Manning	N/A	Purchase	750.00K	$2.75	$2.06M	SEC
Shareholders

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Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
venBio Select Advisor LLC	23.89M	Jun 30, 2026	7.35%	$1.46	10.09%
RA Capital Management, LLC	23.56M	Jun 30, 2026	7.25%	$1.39	0.00%
The Goldman Sachs Group Inc	22.71M	Jun 30, 2026	6.99%	$0.01	1.54%
BlackRock Inc	20.69M	Jun 30, 2026	6.37%	$0.00	12.67%
Vestal Point Capital LP	19.42M	Jun 30, 2026	5.98%	$3.09	7.86%
Morgan Stanley - Brokerage Accounts	16.49M	Jun 30, 2026	5.08%	$0.01	-8.23%
RTW INVESTMENTS, LLC	13.56M	Jun 30, 2026	4.17%	$0.79	-0.88%
FMR Inc	13.34M	Jun 30, 2026	4.11%	$0.00	-6.88%
Vanguard Capital Management, LLC	12.48M	Jun 30, 2026	3.84%	$0.00	21.96%
State Street Corp	11.42M	Jun 30, 2026	3.52%	$0.00	1.90%
Siren, L.L.C.	9.85M	Jun 30, 2026	3.03%	$1.36	11.51%
Octagon Capital Advisors LP	9.69M	Jun 30, 2026	2.98%	$5.93	9.41%
Geode Capital Management, LLC	6.56M	Jun 30, 2026	2.02%	$0.00	18.59%
Polar Capital Holdings PLC	5.12M	Jun 30, 2026	1.58%	$0.08	-9.50%
MPM Oncology Impact Management LP	4.50M	Jun 30, 2026	1.39%	$1.87	0.00%
D. E. Shaw & Co LP	4.40M	Jun 30, 2026	1.35%	$0.01	-0.65%
Baker Bros Advisors LP	4.00M	Jun 30, 2026	1.23%	$0.14	0.00%
Wellington Management Company LLP	3.98M	Jun 30, 2026	1.22%	$0.00	534.71%
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	3.89M	Jun 30, 2026	1.20%	$0.04	34.76%
Casdin Capital, LLC	3.25M	Jun 30, 2026	1.00%	$1.11	0.00%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Vanguard MStar Total Stk Mkt Idx Invest	9.19M	2.83%	▲ 0.21%	Sep 30, 2026
2	iShares Russell 2000 ETF	6.71M	2.07%	▼ 0.41%	Oct 29, 2026
3	State Street® SPDR® S&P® Biotech ETF	5.37M	1.65%	▼ 0.80%	Oct 29, 2026
4	Polar Capital Biotech S Inc	4.85M	1.49%	▲ 0.00%	Sep 30, 2026
5	Fidelity Growth Company Fund	4.17M	1.28%	▲ 0.00%	Aug 31, 2026
6	Fidelity Small Cap Index	2.62M	0.81%	▲ 0.86%	Jul 31, 2026
7	iShares Russell 2000 Growth ETF	2.51M	0.77%	▲ 0.25%	Oct 29, 2026
8	Pictet-Biotech P USD	2.25M	0.69%	▲ 43.24%	Jul 31, 2026
9	abrdn Life Sciences Investors	2.15M	0.66%	▲ 14.44%	Sep 30, 2026
10	iShares Biotechnology ETF	2.06M	0.64%	▼ 0.19%	Oct 29, 2026
Financial Highlights

▼
Market Cap: $1.42B
EBITDA: $-151.99M
Book Value: $1.19
Earnings/Share: $-0.41
Profit Margin: 0.00%
Operating Margin: -2,792.33%
ROA (TTM): -23.82%
ROE (TTM): -47.06%
Revenue (TTM): $5.49M
Revenue/Share (TTM): $0.02
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 171.30%
Valuation Metrics

Enterprise Value: $935.60M
Trailing P/E: 0.00
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 325.83M
Shares Float: 232.62M
% Insiders: 9.45%
% Institutions: 94.56%
Shares Short: 51.25M
Shares Short (Prior Month): 55.02M
Short Ratio: 10.79
Short % Float: 15.98%
Stock Price History

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Open price histogram Stock regimes
1 Year Price History

3 Years Price History

10 Years Price History

Max Price History

Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$9.77M
Cost of Goods Sold
adjust
$-1.15M
Gross Profit
subtotal
$9.77M
SG&A
adjust
$-33.87M
R&D
adjust
$-86.40M
Operating Income
subtotal
$-110.50M
Other / Non-Operating Items
adjust
$1.50M
Net Income
subtotal
$-109.00M
Earnings Per Share (EPS) History

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Financial Ratios

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📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "TSHA",
        "Type": "Common Stock",
        "Name": "Taysha Gene Therapies\u00a0Inc",
        "Exchange": "NASDAQ",
        "OperatingMIC": "XNAS",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG00TJXFDP1",
        "ISIN": null,
        "LEI": null,
        "PrimaryTicker": "TSHA.US",
        "CUSIP": null,
        "CIK": "0001806310",
        "EmployerIdNumber": null,
        "FiscalYearEnd": "December",
        "IPODate": "2020-09-24",
        "InternationalDomestic": null,
        "Sector": "Healthcare",
        "Industry": "Biotechnology",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Biotechnology",
        "GicSubIndustry": "Biotechnology",
        "HomeCategory": null,
        "IsDelisted": false,
        "Description": "Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; and TSHA-114 for the treatment of fragile X syndrome. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.",
        "Address": "3000 Pegasus Park Drive, Dallas, TX, United States, 75247",
        "AddressData": {
            "Street": "3000 Pegasus Park Drive",
            "City": "Dallas",
            "State": "TX",
            "Country": "United States",
            "ZIP": "75247"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Mr. Sean P. Nolan",
                "Title": "CEO & Chairman",
                "YearBorn": "1968"
            },
            {
                "Name": "Dr. Sukumar  Nagendran M.D.",
                "Title": "President, Head of Research & Development and Director",
                "YearBorn": "1967"
            },
            {
                "Name": "Mr. Kamran  Alam CPA, M.B.A.",
                "Title": "CFO & Corporate Secretary",
                "YearBorn": "1978"
            },
            {
                "Name": "Hayleigh  Collins",
                "Title": "Director of Corporate Communications & Investor Relations",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. Michael B. Johannesen",
                "Title": "Chief Legal Officer & Corporate Secretary",
                "YearBorn": "1966"
            },
            {
                "Name": "Mr. Frederick  Porter Ph.D.",
                "Title": "Chief of Staff & Technical Operations Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Ms. Emily  McGinnis M.P.H.",
                "Title": "Chief Patient & External Affairs Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. Sean  McAuliffe",
                "Title": "Chief Business Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Steven  Gray Ph.D.",
                "Title": "Chief Scientific Advisor of UT Southwestern Gene Therapy Program",
                "YearBorn": "NA"
            },
            {
                "Name": "Berge  Minassian M.D.",
                "Title": "Chief Medical Advisor of UT Southwestern Gene Therapy Program",
                "YearBorn": "NA"
            }
        ],
        "Phone": "214 612 0000",
        "WebURL": "https://www.tayshagtx.com",
        "LogoURL": "/img/logos/US/TSHA.png",
        "FullTimeEmployees": 99,
        "UpdatedAt": "2026-11-05"
    },
    "Highlights": {
        "MarketCapitalization": 1420634240,
        "MarketCapitalizationMln": 1420.6342,
        "EBITDA": -151988000,
        "PERatio": null,
        "PEGRatio": null,
        "WallStreetTargetPrice": 13,
        "BookValue": 1.19,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": -0.41,
        "EPSEstimateCurrentYear": -0.474,
        "EPSEstimateNextYear": -0.4625,
        "EPSEstimateNextQuarter": -0.12,
        "EPSEstimateCurrentQuarter": -0.1075,
        "MostRecentQuarter": "2026-06-30",
        "ProfitMargin": 0,
        "OperatingMarginTTM": -27.9233,
        "ReturnOnAssetsTTM": -0.2382,
        "ReturnOnEquityTTM": -0.4706,
        "RevenueTTM": 5485000,
        "RevenuePerShareTTM": 0.015,
        "QuarterlyRevenueGrowthYOY": 1.713,
        "GrossProfitTTM": 5485000,
        "DilutedEpsTTM": -0.41,
        "QuarterlyEarningsGrowthYOY": 0
    },
    "Valuation": {
        "TrailingPE": 0,
        "ForwardPE": 0,
        "PriceSalesTTM": 259.0035,
        "PriceBookMRQ": 3.4454,
        "EnterpriseValue": 935595366,
        "EnterpriseValueRevenue": 170.5734,
        "EnterpriseValueEbitda": -0.6061
    },
    "SharesStats": {
        "SharesOutstanding": 325833545,
        "SharesFloat": 232619084,
        "PercentInsiders": 9.447,
        "PercentInstitutions": 94.563,
        "SharesShort": 51249292,
        "SharesShortPriorMonth": 55020663,
        "ShortRatio": 10.79,
        "ShortPercentOutstanding": null,
        "ShortPercentFloat": 0.1598
    },
    "Technicals": {
        "Beta": 1.313,
        "52WeekHigh": 7.3,
        "52WeekLow": 3.455,
        "50DayMA": 4.7427,
        "200DayMA": 5.3178,
        "SharesShort": 51249292,
        "SharesShortPriorMonth": 55020663,
        "ShortRatio": 10.79,
        "ShortPercent": 0.1598
    },
    "SplitsDividends": {
        "ForwardAnnualDividendRate": 0,
        "ForwardAnnualDividendYield": 0,
        "PayoutRatio": 0,
        "DividendDate": null,
        "ExDividendDate": null,
        "LastSplitFactor": "",
        "LastSplitDate": "0000-00-00",
        "NumberDividendsByYear": []
    },
    "AnalystRatings": {
        "Rating": 4.7692,
        "TargetPrice": 13,
        "StrongBuy": 10,
        "Buy": 3,
        "Hold": 0,
        "Sell": 0,
        "StrongSell": 0
    },
    "Holders": {
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                "name": "venBio Select Advisor LLC",
                "date": "2026-06-30",
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                "change": 2188888,
                "change_p": 10.087
            },
            {
                "name": "RA Capital Management, LLC",
                "date": "2026-06-30",
                "totalShares": 7.251,
                "totalAssets": 1.394,
                "currentShares": 23555648,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "The Goldman Sachs Group Inc",
                "date": "2026-06-30",
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                "totalAssets": 0.0134,
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                "change": 343473,
                "change_p": 1.5354
            },
            {
                "name": "BlackRock Inc",
                "date": "2026-06-30",
                "totalShares": 6.3695,
                "totalAssets": 0.0021,
                "currentShares": 20691927,
                "change": 2326319,
                "change_p": 12.6667
            },
            {
                "name": "Vestal Point Capital LP",
                "date": "2026-06-30",
                "totalShares": 5.9764,
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                "currentShares": 19415000,
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            },
            {
                "name": "Morgan Stanley - Brokerage Accounts",
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                "name": "RTW INVESTMENTS, LLC",
                "date": "2026-06-30",
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                "change": -119990,
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            {
                "name": "FMR Inc",
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            },
            {
                "name": "Vanguard Capital Management, LLC",
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            },
            {
                "name": "State Street Corp",
                "date": "2026-06-30",
                "totalShares": 3.5159,
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                "currentShares": 11421920,
                "change": 212842,
                "change_p": 1.8988
            },
            {
                "name": "Siren, L.L.C.",
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            {
                "name": "Octagon Capital Advisors LP",
                "date": "2026-06-30",
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            {
                "name": "Geode Capital Management, LLC",
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            },
            {
                "name": "Polar Capital Holdings PLC",
                "date": "2026-06-30",
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            },
            {
                "name": "MPM Oncology Impact Management LP",
                "date": "2026-06-30",
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                "change_p": 0
            },
            {
                "name": "D. E. Shaw & Co LP",
                "date": "2026-06-30",
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            },
            {
                "name": "Baker Bros Advisors LP",
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            {
                "name": "Wellington Management Company LLP",
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            {
                "name": "HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND",
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            },
            {
                "name": "Casdin Capital, LLC",
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                "change": 0,
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            }
        ],
        "Funds": [
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                "name": "Vanguard MStar Total Stk Mkt Idx Invest",
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                "change": 18932,
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            },
            {
                "name": "iShares Russell 2000 ETF",
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            },
            {
                "name": "State Street\u00ae SPDR\u00ae S&P\u00ae Biotech ETF",
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                "currentShares": 5370112,
                "change": -43494,
                "change_p": -0.8034
            },
            {
                "name": "Polar Capital Biotech S Inc",
                "date": "2026-09-30",
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                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity Growth Company Fund",
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            },
            {
                "name": "Pictet-Biotech P USD",
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                "change": 678995,
                "change_p": 43.2423
            },
            {
                "name": "abrdn Life Sciences Investors",
                "date": "2026-09-30",
                "totalShares": 0.6612,
                "totalAssets": 1.6824,
                "currentShares": 2148089,
                "change": 271073,
                "change_p": 14.4417
            },
            {
                "name": "iShares Biotechnology ETF",
                "date": "2026-10-29",
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                "totalAssets": 0.0756,
                "currentShares": 2064528,
                "change": -3906,
                "change_p": -0.1888
            },
            {
                "name": "Vanguard Russell 2000 ETF",
                "date": "2026-09-30",
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                "currentShares": 1551256,
                "change": 172476,
                "change_p": 12.5093
            },
            {
                "name": "Schwab US Small-Cap ETF\u2122",
                "date": "2026-10-30",
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                "currentShares": 1451162,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity Extended Market Index",
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                "change": -10106,
                "change_p": -0.7723
            },
            {
                "name": "Fidelity Enhanced Small Cap Core ETF",
                "date": "2026-10-29",
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                "totalAssets": 0.0775,
                "currentShares": 1258096,
                "change": 3392,
                "change_p": 0.2703
            },
            {
                "name": "Fidelity Growth Company K6",
                "date": "2026-08-31",
                "totalShares": 0.3396,
                "totalAssets": 0.0223,
                "currentShares": 1103258,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "abrdn Healthcare Investors",
                "date": "2026-09-30",
                "totalShares": 0.3291,
                "totalAssets": 0.4333,
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}
Taysha Gene Therapies Inc

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